Untuk menjalankan script Python sebagai Daemon gunakan konfigurasi ini:

[program:dnhbot]
directory = /opt/telegram/dnhbot
command = /usr/bin/python3 /opt/telegram/dnhbot/bot.py
startsecs = 0
autorestart = true
stderr_logfile=/var/log/dnhbot.err.log
stdout_logfile=/var/log/dnhbot.out.log

sudo supervisorctl reread && 
sudo supervisorctl update && 
sudo supervisorctl status

Referensi

• https://stackoverflow.com/questions/33738461/supervisord-throws-error-couldnt-exec-var-application-gunicorn-start-enoexe
• https://stackoverflow.com/questions/32737493/run-a-python-script-with-supervisor?answertab=oldest#tab-top